CHRNB2 polyclonal, anti-human, mouse, rat

Background:
Neuronal acetylcholine receptors are homo- or heteropentameric complexes composed of homologous alpha and beta subunits. They belong to a superfamily of ligand-gated ion channels which allow the flow of sodium and potassium across the plasma membrane in response to ligands such as acetylcholine and nicotine. This gene encodes one of several beta subunits. Mutations in this gene are associated with autosomal dominant nocturnal frontal lobe epilepsy.

Synonyms: EFNL3, nAChRB2

Cellular Location: Cell junction Cell membrane Multi-pass membrane protein postsynaptic cell membrane synapse

Immunogen:
Recombinant protein of human CHRNB2

Gene Symbol: CHRNB2

Gene ID: 1141

Swiss prot: P17787

Calculated MW: 57kDa

Recommended dilution:
WB 1:500-2000, IHC 1:50-100,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.