CHRNE polyclonal, anti-human, mouse, rat

Background:
Acetylcholine receptors at mature mammalian neuromuscular junctions are pentameric protein complexes composed of four subunits in the ratio of two alpha subunits to one beta, one epsilon, and one delta subunit. The acetylcholine receptor changes subunit composition shortly after birth when the epsilon subunit replaces the gamma subunit seen in embryonic receptors. Mutations in the epsilon subunit are associated with congenital myasthenic syndrome.

Synonyms: ACHRE, CMS1D, CMS1E, CMS2A, CMS4A, CMS4B, CMS4C, FCCMS, SCCMS

Cellular Location: Cell junction Cell membrane Multi-pass membrane protein postsynaptic cell membrane synapse

Immunogen:
Recombinant protein of human CHRNE

Gene Symbol: CHRNE

Gene ID: 1145

Swiss prot: Q04844

Calculated MW: 55kDa

Recommended dilution:
WB 1:1000-4000

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.