CHRNG Antibody (N-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP17105a
Background:
The mammalian muscle-type acetylcholine receptor is atransmembrane pentameric glycoprotein with two alpha subunits, onebeta, one delta, and one epsilon (in adult skeletal muscle) orgamma (in fetal and denervated muscle) subunit. This gene, whichencodes the gamma subunit, is expressed prior to the thirty-thirdweek of gestation in humans. The gamma subunit of the acetylcholinereceptor plays a role in neuromuscular organogenesis and ligandbinding and disruption of gamma subunit expression prevents thecorrect localization of the receptor in cell membranes. Mutationsin this gene cause Escobar syndrome and a lethal form of multiplepterygium syndrome. Muscle-type acetylcholine receptor is the majorantigen in the autoimmune disease myasthenia gravis.
Other Names:
Acetylcholine receptor subunit gamma, CHRNG, ACHRG
Gene Name: CHRNG (HGNC:1967)
Gene ID: 1146
Primary Accession: P07510
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
The mammalian muscle-type acetylcholine receptor is atransmembrane pentameric glycoprotein with two alpha subunits, onebeta, one delta, and one epsilon (in adult skeletal muscle) orgamma (in fetal and denervated muscle) subunit. This gene, whichencodes the gamma subunit, is expressed prior to the thirty-thirdweek of gestation in humans. The gamma subunit of the acetylcholinereceptor plays a role in neuromuscular organogenesis and ligandbinding and disruption of gamma subunit expression prevents thecorrect localization of the receptor in cell membranes. Mutationsin this gene cause Escobar syndrome and a lethal form of multiplepterygium syndrome. Muscle-type acetylcholine receptor is the majorantigen in the autoimmune disease myasthenia gravis.
Other Names:
Acetylcholine receptor subunit gamma, CHRNG, ACHRG
Gene Name: CHRNG (HGNC:1967)
Gene ID: 1146
Primary Accession: P07510
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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