Chromogranin A polyclonal, anti-human, mouse, rat

Background:
Chromogranin A is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is located in secretory vesicles of neurons and endocrine cells. Chromogranin A is the precursor to several functional peptides including vasostatin, pancreastatin, catestatin and parastatin. These peptides negatively modulate the neuroendocrine function of the releasing cell (autocrine) or nearby cells (paracrine). Chromogranin A might promote the generation of secretory granules. It is used as an indicator for pancreas and prostate cancer. It might play a role in early neoplasic progression. It is also elevated in diabetes.

Alternative Name:
CgA, CISY, Citrate synthase, Citrate synthase, mitochondrial, citrate synthetase, Cs, EC 2.3.3, EC 2.3.3.1,

Application Dilution:
WB:1:2,000
IHC:1:200
FC:1:100-1:200

Specificity: Chromogranin A polyclonal antibody detects endogenous levels of Chromogranin A protein.

Immunogen:
peptide

MW: 86 kDa

Swiss-Prot: P26339

Purification & Purity:
Peptide affinity purified

Format:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Storage:
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

For research use only, not for use in diagnostic procedure.