CHST6 polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS61148
Background:
Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs and xenobiotic compounds. These enzymes differ in their tissue distributions and substrate specificities, although the gene structure (number and length of exons) is similar among family members. Carbohydrate sulfotransferase 5 (CHST5) (also referred to as GlcNAc6ST-3 or IGn6ST) and carbohydrate sulfotransferase 6 (CHST6) (also referred to as GlcNAc6ST-5 or Cgn6ST) are predominantly expressed in the intestine and cornea, respectively. They are highly homologous and both are orthologs of the murine CHST5. CHST5 and CHST6 may be the result of gene duplication. They catalyze the transfer of sulfate to position 6 of non-reducing N-acetylglucosamine (GlcNAc) residues. CHST5 preferably mediates the sulfation of short carbohydrates and O-linked sugars of mucin-type acceptors. CHST6 mediates the sulfation of keratan in the cornea, which is important in maintaining corneal transparency.
Alternative Name:
Carbohydrate sulfotransferase 6 (EC:2.8.2.-), Corneal N-acetylglucosamine-6-O-sulfotransferase, C-GlcNAc6ST, hCGn6ST, Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 4-beta, GST4-beta, N-acetylglucosamine 6-O-sulfotransferase 5, GlcNAc6ST-5, Gn6st-5, CHST6
Application Dilution: WB: 1:500~1:1000
Specificity: CHST6 polyclonal antibody detects endogenous levels of CHST6 protein.
Immunogen:
A synthetic peptide corresponding to residues in Human CHST6.
MW: ~ 44 kDa
Swis Prot.: Q9GZX3
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs and xenobiotic compounds. These enzymes differ in their tissue distributions and substrate specificities, although the gene structure (number and length of exons) is similar among family members. Carbohydrate sulfotransferase 5 (CHST5) (also referred to as GlcNAc6ST-3 or IGn6ST) and carbohydrate sulfotransferase 6 (CHST6) (also referred to as GlcNAc6ST-5 or Cgn6ST) are predominantly expressed in the intestine and cornea, respectively. They are highly homologous and both are orthologs of the murine CHST5. CHST5 and CHST6 may be the result of gene duplication. They catalyze the transfer of sulfate to position 6 of non-reducing N-acetylglucosamine (GlcNAc) residues. CHST5 preferably mediates the sulfation of short carbohydrates and O-linked sugars of mucin-type acceptors. CHST6 mediates the sulfation of keratan in the cornea, which is important in maintaining corneal transparency.
Alternative Name:
Carbohydrate sulfotransferase 6 (EC:2.8.2.-), Corneal N-acetylglucosamine-6-O-sulfotransferase, C-GlcNAc6ST, hCGn6ST, Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 4-beta, GST4-beta, N-acetylglucosamine 6-O-sulfotransferase 5, GlcNAc6ST-5, Gn6st-5, CHST6
Application Dilution: WB: 1:500~1:1000
Specificity: CHST6 polyclonal antibody detects endogenous levels of CHST6 protein.
Immunogen:
A synthetic peptide corresponding to residues in Human CHST6.
MW: ~ 44 kDa
Swis Prot.: Q9GZX3
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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