Tau (clone 10E3), anti-human, mouse, rat
€470.00
In stock
SKU
AC-AP63781
Background:
Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N- terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
Other Names:
MAPT
Antigen Type: synthetic peptide
Antigen Type: MAPT (HGNC:6893)
Gene ID: 4137
Primary Accession: P10636
Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N- terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
Other Names:
MAPT
Antigen Type: synthetic peptide
Antigen Type: MAPT (HGNC:6893)
Gene ID: 4137
Primary Accession: P10636
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