cIAP-1/HIAP-2 polyclonal, anti-human, mouse, rat antibody
€310.00
In stock
SKU
AC-ABV10147-100
Catalog Number: AC-ABV10147-100
Size: 100 µg
Host: Rabbit IgG
Applications: WB, IHC
Datasheet
Request Information
Size: 100 µg
Host: Rabbit IgG
Applications: WB, IHC
Datasheet
Request Information
Background:
Apoptosis can be inhibited by a group of proteins called inhibitors of apoptosis (IAPs). These proteins contain a BIR (baculovirus IAP repeat) domain near the amino-terminus. The BIR domain can bind some caspases. Many members of the IAP family of proteins block proteolytic activation of caspase-3 and –7. For example, XIAP, cIAP-1 and cIAP-2 appear to block cytochrome c-induced activation of caspase-9, thereby preventing initiation of the caspase cascade. Since cIAP-1 and cIAP-2 were first identified as components in the cytosolic death domain-induced complex associated with the TNF family of receptors, they may inhibit apoptosis by additional mechanisms.
Other Names:
API1 , cIAP1, C-IAP1 , HIAP-2 , HIAP2 , RNF48 , MIHB, IAP2, BIRC2
Primary Accession: Q13490
Gene Name: BIRC2
Gene ID: 329
Concentration (mg/ml): 0.2 mg/ml
Apoptosis can be inhibited by a group of proteins called inhibitors of apoptosis (IAPs). These proteins contain a BIR (baculovirus IAP repeat) domain near the amino-terminus. The BIR domain can bind some caspases. Many members of the IAP family of proteins block proteolytic activation of caspase-3 and –7. For example, XIAP, cIAP-1 and cIAP-2 appear to block cytochrome c-induced activation of caspase-9, thereby preventing initiation of the caspase cascade. Since cIAP-1 and cIAP-2 were first identified as components in the cytosolic death domain-induced complex associated with the TNF family of receptors, they may inhibit apoptosis by additional mechanisms.
Other Names:
API1 , cIAP1, C-IAP1 , HIAP-2 , HIAP2 , RNF48 , MIHB, IAP2, BIRC2
Primary Accession: Q13490
Gene Name: BIRC2
Gene ID: 329
Concentration (mg/ml): 0.2 mg/ml
| Is Featured? | No |
|---|
Write Your Own Review