CIDEA Antibody (C-term) Blocking peptide
€363.00
In stock
SKU
AC-BP14057b
Background:
This gene encodes the homolog of the mouse protein Cideathat has been shown to activate apoptosis. This activation ofapoptosis is inhibited by the DNA fragmentation factor DFF45 butnot by caspase inhibitors. Mice that lack functional Cidea havehigher metabolic rates, higher lipolysis in brown adipose tissueand higher core body temperatures when subjected to cold. Thesemice are also resistant to diet-induced obesity and diabetes. Thissuggests that in mice this gene product plays a role inthermogenesis and lipolysis. Alternatively spliced transcripts havebeen identified.
Other Names:
Cell death activator CIDE-A, Cell death-inducing DFFA-like effector A, CIDEA
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP14057b was selected from the C-term region of CIDEA. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: CIDEA {ECO:0000303|PubMed:18509062, ECO:0000312|HGNC:HGNC:1976}
Gene ID: 1149
Primary Accession: O60543
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
This gene encodes the homolog of the mouse protein Cideathat has been shown to activate apoptosis. This activation ofapoptosis is inhibited by the DNA fragmentation factor DFF45 butnot by caspase inhibitors. Mice that lack functional Cidea havehigher metabolic rates, higher lipolysis in brown adipose tissueand higher core body temperatures when subjected to cold. Thesemice are also resistant to diet-induced obesity and diabetes. Thissuggests that in mice this gene product plays a role inthermogenesis and lipolysis. Alternatively spliced transcripts havebeen identified.
Other Names:
Cell death activator CIDE-A, Cell death-inducing DFFA-like effector A, CIDEA
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP14057b was selected from the C-term region of CIDEA. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: CIDEA {ECO:0000303|PubMed:18509062, ECO:0000312|HGNC:HGNC:1976}
Gene ID: 1149
Primary Accession: O60543
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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