CIDEA polyclonal, anti-human
€295.00
In stock
SKU
K005373P
Catalog Number: K005373P
Size: 100 μl
Other size: 50 μl
Isotype: Rabbit IgG
Applications: IF
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Size: 100 μl
Other size: 50 μl
Isotype: Rabbit IgG
Applications: IF
Request Manual
Questions? Contact us!
Background:
This gene encodes the homolog of the mouse protein Cidea that has been shown to activate apoptosis. This activation of apoptosis is inhibited by the DNA fragmentation factor DFF45 but not by caspase inhibitors. Mice that lack functional Cidea have higher metabolic rates, higher lipolysis in brown adipose tissue and higher core body temperatures when subjected to cold. These mice are also resistant to diet-induced obesity and diabetes. This suggests that in mice this gene product plays a role in thermogenesis and lipolysis. Alternatively spliced transcripts have been identified.
Synonyms: CIDE-A
Cellular Location: Lipid droplet Nucleus
Immunogen:
Recombinant protein of human CIDEA
Gene Symbol: CIDEA
Gene ID: 1149
Swiss prot: O60543
Calculated MW: 25kDa
Recommended dilution:
IF 1:50-100
Purity:
Affinity purification
Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at -20℃. Avoid freeze / thaw cycles.
This gene encodes the homolog of the mouse protein Cidea that has been shown to activate apoptosis. This activation of apoptosis is inhibited by the DNA fragmentation factor DFF45 but not by caspase inhibitors. Mice that lack functional Cidea have higher metabolic rates, higher lipolysis in brown adipose tissue and higher core body temperatures when subjected to cold. These mice are also resistant to diet-induced obesity and diabetes. This suggests that in mice this gene product plays a role in thermogenesis and lipolysis. Alternatively spliced transcripts have been identified.
Synonyms: CIDE-A
Cellular Location: Lipid droplet Nucleus
Immunogen:
Recombinant protein of human CIDEA
Gene Symbol: CIDEA
Gene ID: 1149
Swiss prot: O60543
Calculated MW: 25kDa
Recommended dilution:
IF 1:50-100
Purity:
Affinity purification
Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at -20℃. Avoid freeze / thaw cycles.
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