CIDEA Polyclonal Antibody

Background:
This gene encodes the homolog of the mouse protein Cidea that has been shown to activate apoptosis. This activation of apoptosis is inhibited by the DNA fragmentation factor DFF45 but not by caspase inhibitors. Mice that lack functional Cidea have higher metabolic rates, higher lipolysis in brown adipose tissue and higher core body temperatures when subjected to cold. These mice are also resistant to diet-induced obesity and diabetes. This suggests that in mice this gene product plays a role in thermogenesis and lipolysis. Alternatively spliced transcripts have been identified.

Research Area: Cancer, Cell Biology, Cardiovascular, Epigenetics and Nuclear Signaling, Metabolism

Synonyms:
CIDEA, CIDE-A

Immunogen: Recombinant fusion protein of human CIDEA (NP_001270.1).

Swissprot: O60543
Gene ID: 1149

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: IF 1:50-1:100

Storage:
Store at -20°C. Avoid freeze / thaw cycles.