CIDEA polyclonal (C-term), anti-human
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In stock
SKU
AC-AP14057b
Catalog Number: AC-AP14057b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB34139
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB34139
Applications: WB
Datasheet
Request Information
Background:
This gene encodes the homolog of the mouse protein Cidea that has been shown to activate apoptosis. This activation of apoptosis is inhibited by the DNA fragmentation factor DFF45 but not by caspase inhibitors. Mice that lack functional Cidea have higher metabolic rates, higher lipolysis in brown adipose tissue and higher core body temperatures when subjected to cold. These mice are also resistant to diet-induced obesity and diabetes. This suggests that in mice this gene product plays a role in thermogenesis and lipolysis. Alternatively spliced transcripts have been identified.
Other Names:
Cell death activator CIDE-A, Cell death-inducing DFFA-like effector A, CIDEA
Target/Specificity:
This CIDEA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 181-209 amino acids from the C-terminal region of human CIDEA.
Antigen Region:
181-209
Antigen Type: Synthetic Peptide
Gene Name: CIDEA {ECO:0000303|PubMed:18509062, ECO:0000312|HGNC:HGNC:1976}
Gene ID: 1149
Primary Accession: O60543
NCBI Accession: NP_001270.1
Other Accession: NP_001270.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
This gene encodes the homolog of the mouse protein Cidea that has been shown to activate apoptosis. This activation of apoptosis is inhibited by the DNA fragmentation factor DFF45 but not by caspase inhibitors. Mice that lack functional Cidea have higher metabolic rates, higher lipolysis in brown adipose tissue and higher core body temperatures when subjected to cold. These mice are also resistant to diet-induced obesity and diabetes. This suggests that in mice this gene product plays a role in thermogenesis and lipolysis. Alternatively spliced transcripts have been identified.
Other Names:
Cell death activator CIDE-A, Cell death-inducing DFFA-like effector A, CIDEA
Target/Specificity:
This CIDEA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 181-209 amino acids from the C-terminal region of human CIDEA.
Antigen Region:
181-209
Antigen Type: Synthetic Peptide
Gene Name: CIDEA {ECO:0000303|PubMed:18509062, ECO:0000312|HGNC:HGNC:1976}
Gene ID: 1149
Primary Accession: O60543
NCBI Accession: NP_001270.1
Other Accession: NP_001270.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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