CIT Antibody (C-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP7124b
Background:
CIT is a putative RHO/RAC effector that binds to the GTP-bound forms of RHO and RAC1. It probably binds p21 with a tighter specificity in vivo. This protein exhibits dual specificity protein kinase activity catalyzing autophosphorylation and phosphorylation of exogenous substrates on both serine/threonine and tyrosine residues. CIT plays an important role in the regulation of cytokinesis and the development of the central nervous system.
Other Names:
Citron Rho-interacting kinase, CRIK, Serine/threonine-protein kinase 21, CIT, CRIK, KIAA0949, STK21
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP7124b was selected from the C-term region of human CIT. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: CIT
Gene ID: 11113
Primary Accession: O14578
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
CIT is a putative RHO/RAC effector that binds to the GTP-bound forms of RHO and RAC1. It probably binds p21 with a tighter specificity in vivo. This protein exhibits dual specificity protein kinase activity catalyzing autophosphorylation and phosphorylation of exogenous substrates on both serine/threonine and tyrosine residues. CIT plays an important role in the regulation of cytokinesis and the development of the central nervous system.
Other Names:
Citron Rho-interacting kinase, CRIK, Serine/threonine-protein kinase 21, CIT, CRIK, KIAA0949, STK21
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP7124b was selected from the C-term region of human CIT. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: CIT
Gene ID: 11113
Primary Accession: O14578
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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