CIT polyclonal (Center), anti-human
€0.00
In stock
SKU
AC-AP7124a
Catalog Number: AC-AP7124a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB5388
Applications: IHC-P
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB5388
Applications: IHC-P
Datasheet
Request Information
Background:
CIT is a putative RHO/RAC effector that binds to the GTP-bound forms of RHO and RAC1. It probably binds p21 with a tighter specificity in vivo. This protein exhibits dual specificity protein kinase activity catalyzing autophosphorylation and phosphorylation of exogenous substrates on both serine/threonine and tyrosine residues. CIT plays an important role in the regulation of cytokinesis and the development of the central nervous system.
Other Names:
Citron Rho-interacting kinase, CRIK, Serine/threonine-protein kinase 21, CIT, CRIK, KIAA0949, STK21
Target/Specificity:
This CIT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human CIT.
Gene Name: CIT
Gene ID: 11113
Primary Accession: O14578
NCBI Accession: NP_001193928.1;NP_009105.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
CIT is a putative RHO/RAC effector that binds to the GTP-bound forms of RHO and RAC1. It probably binds p21 with a tighter specificity in vivo. This protein exhibits dual specificity protein kinase activity catalyzing autophosphorylation and phosphorylation of exogenous substrates on both serine/threonine and tyrosine residues. CIT plays an important role in the regulation of cytokinesis and the development of the central nervous system.
Other Names:
Citron Rho-interacting kinase, CRIK, Serine/threonine-protein kinase 21, CIT, CRIK, KIAA0949, STK21
Target/Specificity:
This CIT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human CIT.
Gene Name: CIT
Gene ID: 11113
Primary Accession: O14578
NCBI Accession: NP_001193928.1;NP_009105.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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