CK-16 Polyclonal Antibody

Background:
The protein encoded by this gene is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains and are clustered in a region of chromosome 17q12-q21. This keratin has been coexpressed with keratin 14 in a number of epithelial tissues, including esophagus, tongue, and hair follicles. Mutations in this gene are associated with type 1 pachyonychia congenita, non-epidermolytic palmoplantar keratoderma and unilateral palmoplantar verrucous nevus.

Research Area: Cancer, Signal Transduction

Synonyms:
CK 16, CK-16, CK16, Cytokeratin-16, Cytokeratin16, FNEPPK, Focal non epidermolytic palmoplantar keratoderma, K 16, K16, K1C16, K1CP, Keratin 1 type I, Keratin 16, Keratin, Keratin type I cytoskeletal 16, Keratin-16, Keratin16, KRT 16, Krt16, KRT16A, NEPPK, PC1, type I cytoskeletal 16

Immunogen: Synthetic peptide of human KRT16

Swissprot: P08779
Gene Accession: NP_005548

Calculated MW: 51 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.6 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-49176