CK-18 Monoclonal Antibody

Background:
Involved in the uptake of thrombin-antithrombin complexes by hepatic cells (By similarity). When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection.

Research Area: Cancer, Signal Transduction, Tags and Cell Markers

Synonyms:
Cell proliferation inducing gene 46 protein, Cell proliferation inducing protein 46, Cell proliferation-inducing gene 46 protein, CK 18, CK-18, CK18, CYK 18, CYK18, Cytokeratin 18, Cytokeratin endo B, Cytokeratin-18, K 18, K18, K1C18, KA18, Keratin 18, Keratin 18, type I, Keratin D, keratin, type I cytoskeletal 18, Keratin-18, Krt18

Immunogen: Recombinant Protein

Swissprot: P05783

Calculated MW: 48 kDa
Observed MW: 46 kDa

Purification Method: Protein A purification

Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.4.

Concentration: 1 mg/mL
Dilution: WB 1:1000-3000, IF 1:100-200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.