CKAP4 Polyclonal Antibody

Background:
CKAP4 (cytoskeleton-associated protein 4), also known as p63, CLIMP-63 or ERGIC-63, is a 602 amino acid single-pass type II transmembrane protein that links the endoplasmic reticulum (ER) to the cytoskeleton. Considered a novel protein in maintaining ER morphology, CKAP4 anchors the ER to microtubles which is required for maintaining ER spatial distribution during interphase of the cell cycle. CKAP4 can be reversibly palmitoylated and phosphorylated and is a major substrate of the palmitoyl acyltransferase, ZDHHC2.

Research Area: Cancer

Synonyms:
63 kDa membrane protein, CKAP 4, Ckap4, CKAP4, Cytoskeleton associated protein 4, Cytoskeleton-associated protein 4, ERGIC 63, ERGIC63, MGC99554, p63, Transmembrane protein 63kD endoplasmic reticulum Golgi intermediate compartment, Type II transmembrane protein p63

Immunogen: Synthetic peptide of human CKAP4

Swissprot: Q07065
Gene Accession: NP_006816

Calculated MW: 66 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.6 mg/mL
Dilution: WB 1:1000-1:5000, IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-167469