CKMT2 Polyclonal Antibody

Background:
Mitochondrial creatine kinase (MtCK) is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Sarcomeric mitochondrial creatine kinase has 80% homology with the coding exons of ubiquitous mitochondrial creatine kinase. This gene contains sequences homologous to several motifs that are shared among some nuclear genes encoding mitochondrial proteins and thus may be essential for the coordinated activation of these genes during mitochondrial biogenesis. Three transcript variants encoding the same protein have been found for this gene.

Research Area: Cancer, Metabolism, Signal Transduction, Tags and Cell Markers

Synonyms:
CKMT 2, Basic-type mitochondrial creatine kinase, CKMT2, CPK, Creatine kinase mitochondrial 2, Creatine kinase mitochondrial 2 (sarcomeric), Creatine kinase S-type, creatine kinase S-type, mitochondrial, Creatine kinase, sarcomeric mitochondrial, KCRS, Mib CK, Mib-CK, mitochondrial, OTTHUMP00000147542, S-MtCK, Sarcomeric mitochondrial creatine kinase, SMTCK

Immunogen: Recombinant protein of human CKMT2

Swissprot: P17540
Gene Accession: BC029140

Calculated MW: 48 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.4 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:100-1:300

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-15167/sc-15168/sc-15169