CLASP1 polyclonal, anti-human, mouse, rat

Background:
Microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules. Involved in the nucleation of noncentrosomal microtubules originating from the trans-Golgi network (TGN). Required for the polarization of the cytoplasmic microtubule arrays in migrating cells towards the leading edge of the cell. May act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching their plus-ends to cortical platforms composed of ERC1 and PHLDB2. This cortical microtubule stabilizing activity is regulated at least in part by phosphatidylinositol 3-kinase signaling. Also performs a similar stabilizing function at the kinetochore which is essential for the bipolar alignment of chromosomes on the mitotic spindle.

Alternative Name:
hOrbit1, CLASP1, KIAA0622, MAST1, 1700030C23Rik, 5730583A19Rik, B130045P17Rik, CLAP1, clasp1, CLIP associating protein 1, CLIP associating protein CLASP1, CLIP-associating protein 1, Cytoplasmic linker associated protein 1, Cytoplasmic linker-associated protein 1, DKFZp686D1968, DKFZp686H2039, FLJ33821, FLJ41222, hOrbit1, KIAA0622, MAST1, MGC131895, mKIAA0622, Multiple asters 1, Multiple asters homolog 1, Protein Orbit homolog 1 antibody

Application Dilution:
WB:1:500-1:2,000
ICC:1:50-1:200
IHC:1:50-1:200
FC:1:50-1:100

Specificity: CLASP1 polyclonal antibody detects endogenous levels of CLASP1 protein.

Immunogen:
Recombinant protein within human CLASP1 aa 1-200.

MW: 169 kDa

Swiss-Prot: Q7Z460 Human,Q80TV8 Mouse,Entrez Gene: 304740 Rat

Purification & Purity:
Protein A purified.

Format:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Storage:
Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.

For research use only, not for use in diagnostic procedure.