CLASP2 polyclonal (C-term), anti-human
€0.00
In stock
SKU
AC-AP7181b
Catalog Number: AC-AP7181b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB9127
Applications: IHC-P, WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB9127
Applications: IHC-P, WB
Datasheet
Request Information
Background:
Microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules. Required for the polarization of the cytoplasmic microtubule arrays in migrating cells towards the leading edge of the cell. May act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching their plus-ends to cortical platforms composed of ERC1 and PHLDB2. This cortical microtubule stabilizing activity is regulated at least in part by phosphatidylinositol 3-kinase signaling. Also performs a similar stabilizing function at the kinetochore which is essential for the bipolar alignment of chromosomes on the mitotic spindle.
Other Names:
CLIP-associating protein 2, Cytoplasmic linker-associated protein 2, Protein Orbit homolog 2, hOrbit2, CLASP2, KIAA0627
Target/Specificity:
This CLASP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 946-975 amino acids from the C-terminal region of human CLASP2.
Antigen Region:
946-975
Antigen Type: Synthetic Peptide
Gene Name: CLASP2
Gene ID: 23122
Primary Accession: O75122
NCBI Accession: NP_001193973.1;NP_055912.2
Other Accession: NP_055912
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules. Required for the polarization of the cytoplasmic microtubule arrays in migrating cells towards the leading edge of the cell. May act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching their plus-ends to cortical platforms composed of ERC1 and PHLDB2. This cortical microtubule stabilizing activity is regulated at least in part by phosphatidylinositol 3-kinase signaling. Also performs a similar stabilizing function at the kinetochore which is essential for the bipolar alignment of chromosomes on the mitotic spindle.
Other Names:
CLIP-associating protein 2, Cytoplasmic linker-associated protein 2, Protein Orbit homolog 2, hOrbit2, CLASP2, KIAA0627
Target/Specificity:
This CLASP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 946-975 amino acids from the C-terminal region of human CLASP2.
Antigen Region:
946-975
Antigen Type: Synthetic Peptide
Gene Name: CLASP2
Gene ID: 23122
Primary Accession: O75122
NCBI Accession: NP_001193973.1;NP_055912.2
Other Accession: NP_055912
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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