CLASP2 polyclonal (Y1019), anti-human, mouse
€0.00
In stock
SKU
AC-AP9035a
Catalog Number: AC-AP9035a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB16644
Applications: FC, WB
Datasheet
Request Information
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB16644
Applications: FC, WB
Datasheet
Request Information
Background:
CLASP2 is microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules. Required for the polarization of the cytoplasmic microtubule arrays in migrating cells towards the leading edge of the cell. May act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching their plus-ends to cortical platforms composed of ERC1 and PHLDB2. This cortical microtubule stabilizing activity is regulated at least in part by phosphatidylinositol 3-kinase signaling. Also performs a similar stabilizing function at the kinetochore which is essential for the bipolar alignment of chromosomes on the mitotic spindle.
Other Names:
CLIP-associating protein 2, Cytoplasmic linker-associated protein 2, Protein Orbit homolog 2, hOrbit2, CLASP2, KIAA0627
Target/Specificity:
This CLASP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 998-1026 amino acids from human CLASP2.
Antigen Region:
998-1026
Antigen Type: Synthetic Peptide
Gene Name: CLASP2
Gene ID: 23122
Primary Accession: O75122
NCBI Accession: NP_001193973.1;NP_055912.2
Other Accession: Q99JD4; Q8BRT1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
CLASP2 is microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules. Required for the polarization of the cytoplasmic microtubule arrays in migrating cells towards the leading edge of the cell. May act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching their plus-ends to cortical platforms composed of ERC1 and PHLDB2. This cortical microtubule stabilizing activity is regulated at least in part by phosphatidylinositol 3-kinase signaling. Also performs a similar stabilizing function at the kinetochore which is essential for the bipolar alignment of chromosomes on the mitotic spindle.
Other Names:
CLIP-associating protein 2, Cytoplasmic linker-associated protein 2, Protein Orbit homolog 2, hOrbit2, CLASP2, KIAA0627
Target/Specificity:
This CLASP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 998-1026 amino acids from human CLASP2.
Antigen Region:
998-1026
Antigen Type: Synthetic Peptide
Gene Name: CLASP2
Gene ID: 23122
Primary Accession: O75122
NCBI Accession: NP_001193973.1;NP_055912.2
Other Accession: Q99JD4; Q8BRT1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
|---|
Write Your Own Review