Clathrin, Light Chain (clone SPM174), anti-human
€0.00
In stock
SKU
AC-AH13119
Catalog Number: AC-AH13119
Size: 20 µg, 100 µg
Isotype: Mouse
Clone Name: SPM174
Applications: WB, IHC-P, IF, FC
Datasheet
Request Information
Size: 20 µg, 100 µg
Isotype: Mouse
Clone Name: SPM174
Applications: WB, IHC-P, IF, FC
Datasheet
Request Information
Background:
Recognizes proteins of 31-44kDa, which are identified as Clathrin Light Chains (both A & B). Clathrin is composed of three heavy chains and three light chains, which associate non-covalently to form a triskelion structure. Clathrin light chain regulates the self-assembly of triskelions onto intracellular membranes. Clathrin light chain subunits (LCA and LCB) contribute to regulation of coated vesicle formation to sort proteins during receptor-mediated endocytosis and organelle biogenesis. LCA and LCB are encoded by two discrete genes. They share only 60% homology, and have certain features in common. Both LCA and LCB undergo alternative mRNA splicing, which results in the generation of tissue-specific isoforms.
Other Names:
Clathrin light chain A; Clathrin light chain B; Clathrin light chain LCA; Clathrin light chain LCB; Clathrin light polypeptide A; Clathrin light polypeptide B; Clathrin, light polypeptide (Lca); Clathrin, light polypeptide (Lcb); CLTA; CLTB
Antigen Type:
Recombinant protein
Gene Name: CLTA
Gene ID: 1211
Primary Accession: P09496
Other Accession: 484241; 522114; 1212,P09497
Recognizes proteins of 31-44kDa, which are identified as Clathrin Light Chains (both A & B). Clathrin is composed of three heavy chains and three light chains, which associate non-covalently to form a triskelion structure. Clathrin light chain regulates the self-assembly of triskelions onto intracellular membranes. Clathrin light chain subunits (LCA and LCB) contribute to regulation of coated vesicle formation to sort proteins during receptor-mediated endocytosis and organelle biogenesis. LCA and LCB are encoded by two discrete genes. They share only 60% homology, and have certain features in common. Both LCA and LCB undergo alternative mRNA splicing, which results in the generation of tissue-specific isoforms.
Other Names:
Clathrin light chain A; Clathrin light chain B; Clathrin light chain LCA; Clathrin light chain LCB; Clathrin light polypeptide A; Clathrin light polypeptide B; Clathrin, light polypeptide (Lca); Clathrin, light polypeptide (Lcb); CLTA; CLTB
Antigen Type:
Recombinant protein
Gene Name: CLTA
Gene ID: 1211
Primary Accession: P09496
Other Accession: 484241; 522114; 1212,P09497
| Is Featured? | No |
|---|
Write Your Own Review