Claudin 1 (CLDN1) polyclonal (Loop1), anti-human
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In stock
SKU
AC-AP6308a
Catalog Number: AC-AP6308a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB13129
Applications: IHC-P, WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB13129
Applications: IHC-P, WB
Datasheet
Request Information
Background:
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. CLDN1, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome.
Other Names:
Claudin-1, Senescence-associated epithelial membrane protein, CLDN1, CLD1, SEMP1
Target/Specificity:
This Claudin 1(CLDN1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 40-82 amino acids from human Claudin 1(CLDN1).
Antigen Region:
40-82
Antigen Type: Synthetic Peptide
Gene Name: CLDN1
Gene ID: 9076
Primary Accession: O95832
NCBI Accession: NP_066924.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. CLDN1, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome.
Other Names:
Claudin-1, Senescence-associated epithelial membrane protein, CLDN1, CLD1, SEMP1
Target/Specificity:
This Claudin 1(CLDN1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 40-82 amino acids from human Claudin 1(CLDN1).
Antigen Region:
40-82
Antigen Type: Synthetic Peptide
Gene Name: CLDN1
Gene ID: 9076
Primary Accession: O95832
NCBI Accession: NP_066924.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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