Claudin-10 Polyclonal Antibody

Background:
claudin 10(CLDN10) Homo sapiens This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. The expression level of this gene is associated with recurrence of primary hepatocellular carcinoma. Six alternatively spliced transcript variants encoding different isoforms have been reported, but the transcript sequences of some variants are not determined.[provided by RefSeq, Jun 2010],

Alternative Names:
CLDN10, Claudin-10, OSP-like protein

Immunogen: The antiserum was produced against synthesized peptide derived from human Claudin 10. AA range:179-228

Isotype: Rabbit

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml

Observed band: 25

GeneID: CLDN10

Storage: -20°C/1 year

NOTE: For Research Use Only