Claudin 3 Polyclonal Antibody

Background:
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this intronless gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is also a low-affinity receptor for Clostridium perfringens enterotoxin, and shares aa sequence similarity with a putative apoptosis-related protein found in rat.

Research Area: Cancer, Metabolism, Signal Transduction

Synonyms:
C7orf1, Claudin-3, Claudin3, CLD3, CLDN 3, Cldn3, Clostridium perfringens enterotoxin receptor 2, CPE R2, CPE receptor 2, CPE-R 2, CPE-receptor 2, CPETR 2, CPETR2, HRVP 1, HRVP1, Rat ventral prostate 1 like protein, Rat ventral prostate.1 protein homolog, RVP1, Ventral prostate.1 like protein, Ventral prostate.1 protein homolog

Immunogen: Synthetic peptide of human CLDN3

Swissprot: O15551
Gene Accession: NP_001297

Calculated MW: 23 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.4 mg/mL
Dilution: WB 1:500-1:2000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-17662/sc-17660