Claudin 4 Polyclonal Antibody

Background:
Claudin 4, also known as CLDN4, is a protein which in humans is encoded by the CLDN4 gene. It belongs to the group of claudins. This gene encodes an integral membrane protein, which belongs to the claudin family. The protein is a component of tight junction strands and may play a role in internal organ development and function during pre- and postnatal life. This gene is deleted in Williams-Beuren syndrome, a neurodevelopmental disorder affecting multiple systems.

Research Area: Cancer, Signal Transduction

Synonyms:
Claudin-4, Claudin4, CLD4, CLDN 4, CLDN4, Clostridium perfringens enterotoxin receptor 1, Clostridium perfringens enterotoxin receptor, CPE R, CPE receptor, CPE-R, CPE-receptor, CPER, CPETR 1, CPETR, CPETR1, hCPE R, WBSCR8, Williams Beuren syndrome chromosome region 8 protein, Williams-Beuren syndrome chromosomal region 8 protein

Immunogen: Synthesized peptide derived from the C-terminal region of human Claudin-4

Swissprot: O14493

Calculated MW: 22 kDa
Observed MW: 22 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4

Concentration: 1 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:5000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.