Claudin 5 Polyclonal Antibody

Background:
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Mutations in this gene have been found in patients with velocardiofacial syndrome. Alternatively spliced transcript variants encoding the same protein have been found for this gene

Research Area: Cancer, Signal Transduction

Synonyms:
Androgen withdrawal and apoptosis induced protein RVP1 like, AWAL, BEC 1, BEC1, Claudin 5 (transmembrane protein deleted in velocardiofacial syndrome), Claudin-5, Claudin5, CLD5, CLDN 5, Cldn5, CPETR L1, CPETRL 1, CPETRL1, TMDVCF, TMVCF, Transmembrane protein deleted in VCFS, Transmembrane protein deleted in velocardiofacial syndrome

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse claudin 5

Swissprot: O00501,O54942

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4

Concentration: 0.74 mg/mL
Dilution: IHC 1:200-1:1000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Citation(s):
https://www.sciencedirect.com/science/article/pii/S0006291X18328110