CLCA2 antibody (clone 1B9), anti-human
€435.00
In stock
SKU
AC-AT1549a
Catalog Number: AC-AT1549a
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB
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Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB
Request Information AC-AT1549a">Request Information
Background:
The protein encoded by this gene belongs to the calcium sensitive chloride conductance protein family. To date, all members of this gene family map to the same site on chromosome 1p31-p22 and share high degrees of homology in size, sequence and predicted structure, but differ significantly in their tissue distributions. Since this protein is expressed predominantly in trachea and lung, it is suggested to play a role in the complex pathogenesis of cystic fibrosis. It may also serve as adhesion molecule for lung metastatic cancer cells, mediating vascular arrest and colonization, and furthermore, it has been implicated to act as a tumor suppressor gene for breast cancer.
Other Names:
Calcium-activated chloride channel regulator 2, 34--, Calcium-activated chloride channel family member 2, hCLCA2, Calcium-activated chloride channel protein 3, CaCC-3, hCaCC-3, Calcium-activated chloride channel regulator 2, 109 kDa form, Calcium-activated chloride channel regulator 2, 35 kDa form, CLCA2, CACC3
Antigen Type:
Recombinant Protein
Gene Name: CLCA2
Gene ID: 9635
NCBI Accession: NP_006527.1
Primary Accession: Q9UQC9
Other Accession: NM_006536
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
The protein encoded by this gene belongs to the calcium sensitive chloride conductance protein family. To date, all members of this gene family map to the same site on chromosome 1p31-p22 and share high degrees of homology in size, sequence and predicted structure, but differ significantly in their tissue distributions. Since this protein is expressed predominantly in trachea and lung, it is suggested to play a role in the complex pathogenesis of cystic fibrosis. It may also serve as adhesion molecule for lung metastatic cancer cells, mediating vascular arrest and colonization, and furthermore, it has been implicated to act as a tumor suppressor gene for breast cancer.
Other Names:
Calcium-activated chloride channel regulator 2, 34--, Calcium-activated chloride channel family member 2, hCLCA2, Calcium-activated chloride channel protein 3, CaCC-3, hCaCC-3, Calcium-activated chloride channel regulator 2, 109 kDa form, Calcium-activated chloride channel regulator 2, 35 kDa form, CLCA2, CACC3
Antigen Type:
Recombinant Protein
Gene Name: CLCA2
Gene ID: 9635
NCBI Accession: NP_006527.1
Primary Accession: Q9UQC9
Other Accession: NM_006536
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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