CLCN5 polyclonal, anti-human, mouse

Background:
This gene encodes a member of the ClC family of chloride ion channels and ion transporters. The encoded protein is primarily localized to endosomal membranes and may function to facilitate albumin uptake by the renal proximal tubule. Mutations in this gene have been found in Dent disease and renal tubular disorders complicated by nephrolithiasis. Alternatively spliced transcript variants have been found for this gene.

Synonyms: CLC5, CLCK2, ClC-5, DENTS, NPHL1, NPHL2, XLRH, XRN, hCIC-K2

Cellular Location: Cell membrane Endosome membrane Golgi apparatus membrane Multi-pass membrane protein

Immunogen:
Recombinant protein of human CLCN5

Gene Symbol: CLCN5

Gene ID: 1184

Swiss prot: P51795

Calculated MW: 83kDa

Recommended dilution:
WB 1:500-2000, IHC 1:50-200, IF 1:20-100,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.