CLCN7 polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS5664
Background:
The family of voltage-dependent chloride channels (CLCs) regulate cellular trafficking of chloride ions, a critical component of all living cells. CLCs regulate excitability in muscle and nerve cells, aid in organic solute transport and maintain cellular volume. The genes encoding human CLC-1 through CLC-7 map to chromosomes 7q32, 3q28, 4q32, Xp22.3, Xp11.23-p11.22, 1p36 and 16p13, respectively. CLC6 and CLC7 are broadly expressed in several tissues including testis, kidney, brain and muscle.
Alternative Name:
H(+)/Cl(-) exchange transporter 7, Chloride channel 7 alpha subunit, Chloride channel protein 7, ClC-7, CLCN7, CLCN-7
Application Dilution: WB: 1:500~1:1000, ICC: 1:50~1:200
Specificity: CLCN7 polyclonal antibody detects endogenous levels of CLCN7 protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 33-78 of Human CLCN7.
MW: ~ 89 kDa
Swis Prot.: P51798
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
The family of voltage-dependent chloride channels (CLCs) regulate cellular trafficking of chloride ions, a critical component of all living cells. CLCs regulate excitability in muscle and nerve cells, aid in organic solute transport and maintain cellular volume. The genes encoding human CLC-1 through CLC-7 map to chromosomes 7q32, 3q28, 4q32, Xp22.3, Xp11.23-p11.22, 1p36 and 16p13, respectively. CLC6 and CLC7 are broadly expressed in several tissues including testis, kidney, brain and muscle.
Alternative Name:
H(+)/Cl(-) exchange transporter 7, Chloride channel 7 alpha subunit, Chloride channel protein 7, ClC-7, CLCN7, CLCN-7
Application Dilution: WB: 1:500~1:1000, ICC: 1:50~1:200
Specificity: CLCN7 polyclonal antibody detects endogenous levels of CLCN7 protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 33-78 of Human CLCN7.
MW: ~ 89 kDa
Swis Prot.: P51798
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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