CLCNKA/CLCNKB Antibody (C-term) Blocking peptide
€363.00
In stock
SKU
AC-BP6358a
Background:
Chloride channel Kb (CLCNKB) is a member of the CLC family of voltage-gated chloride channels, which comprises at least 9 mammalian chloride channels. Each is believed to have 12 transmembrane domains and intracellular N and C termini. Mutations in CLCNKB result in the autosomal recessive Type III Bartter Syndrome. CLCNKA and CLCNKB are closely related (94% sequence identity), tightly linked (separated by 11 kb of genomic sequence) and are both expressed in mammalian kidney.
Other Names:
Chloride channel protein ClC-Kb, Chloride channel Kb, ClC-K2, CLCNKB
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP6358a was selected from the C-term region of human CLCNKB. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: CLCNKB
Gene ID: 1188
Primary Accession: P51801
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Chloride channel Kb (CLCNKB) is a member of the CLC family of voltage-gated chloride channels, which comprises at least 9 mammalian chloride channels. Each is believed to have 12 transmembrane domains and intracellular N and C termini. Mutations in CLCNKB result in the autosomal recessive Type III Bartter Syndrome. CLCNKA and CLCNKB are closely related (94% sequence identity), tightly linked (separated by 11 kb of genomic sequence) and are both expressed in mammalian kidney.
Other Names:
Chloride channel protein ClC-Kb, Chloride channel Kb, ClC-K2, CLCNKB
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP6358a was selected from the C-term region of human CLCNKB. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: CLCNKB
Gene ID: 1188
Primary Accession: P51801
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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