CLDN14 polyclonal (C-term), anti-human
€0.00
In stock
SKU
AC-AP20035b
Catalog Number: AC-AP20035b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB42184
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB42184
Applications: WB
Datasheet
Request Information
Background:
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. The encoded protein also binds specifically to the WW domain of Yes-associated protein. Defects in this gene are the cause of an autosomal recessive form of nonsyndromic sensorineural deafness. It is also reported that four synonymous variants in this gene are associated with kidney stones and reduced bone mineral density. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq].
Other Names:
Claudin-14, CLDN14
Target/Specificity:
This CLDN14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 172-200 amino acids from the C-terminal region of human CLDN14.
Antigen Region:
172-200
Antigen Type: Synthetic Peptide
Gene Name: CLDN14
Gene ID: 23562
Primary Accession: O95500
NCBI Accession: NP_001139549.1;NP_001139550.1;NP_001139551.1;NP_036262.1;NP_652763.1
Other Accession: NP_036262.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. The encoded protein also binds specifically to the WW domain of Yes-associated protein. Defects in this gene are the cause of an autosomal recessive form of nonsyndromic sensorineural deafness. It is also reported that four synonymous variants in this gene are associated with kidney stones and reduced bone mineral density. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq].
Other Names:
Claudin-14, CLDN14
Target/Specificity:
This CLDN14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 172-200 amino acids from the C-terminal region of human CLDN14.
Antigen Region:
172-200
Antigen Type: Synthetic Peptide
Gene Name: CLDN14
Gene ID: 23562
Primary Accession: O95500
NCBI Accession: NP_001139549.1;NP_001139550.1;NP_001139551.1;NP_036262.1;NP_652763.1
Other Accession: NP_036262.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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