CLDN4 polyclonal, anti-human

Background:
The protein encoded by this intronless gene belongs to the claudin family. Claudins are integral membrane proteins that are components of the epithelial cell tight junctions, which regulate movement of solutes and ions through the paracellular space. This protein is a high-affinity receptor for Clostridium perfringens enterotoxin (CPE) and may play a role in internal organ development and function during pre- and postnatal life. This gene is deleted in Williams-Beuren syndrome, a neurodevelopmental disorder affecting multiple systems.

Synonyms: CPE-R, CPER, CPETR, CPETR1, WBSCR8, hCPE-R

Cellular Location: Cell junction Cell membrane Multi-pass membrane protein tight junction

Immunogen:
A synthetic peptide of human CLDN4

Gene Symbol: CLDN4

Gene ID: 1364

Swiss prot: O14493

Calculated MW: 22kDa

Recommended dilution:
WB 1:500-1000

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.