CLDN4 Polyclonal Antibody

Background:
The protein encoded by this intronless gene belongs to the claudin family. Claudins are integral membrane proteins that are components of the epithelial cell tight junctions, which regulate movement of solutes and ions through the paracellular space. This protein is a high-affinity receptor for Clostridium perfringens enterotoxin (CPE) and may play a role in internal organ development and function during pre- and postnatal life. This gene is deleted in Williams-Beuren syndrome, a neurodevelopmental disorder affecting multiple systems.

Research Area: Cancer, Signal Transduction

Synonyms:
CLDN4, CPE-R, CPER, CPETR, CPETR1, WBSCR8, hCPE-R, claudin-4

Immunogen: A synthetic peptide of human CLDN4 (NP_001296.1).

Swissprot: O14493
Gene ID: 1364

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "IHC 1:50-1:100"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.