CLDN7 Antibody (C-term) Blocking peptide

Background:
This gene encodes a member of the claudin family. Claudinsare integral membrane proteins and components of tight junctionstrands. Tight junction strands serve as a physical barrier toprevent solutes and water from passing freely through theparacellular space between epithelial or endothelial cell sheets,and also play critical roles in maintaining cell polarity andsignal transductions. Differential expression of this gene has beenobserved in different types of malignancies, including breastcancer, ovarian cancer, hepatocellular carcinomas, urinary tumors,prostate cancer, lung cancer, head and neck cancers, thyroidcarcinomas, etc.. Alternatively spliced transcript variantsencoding different isoforms have been found.

Other Names:
Claudin-7, CLDN-7, CLDN7, CEPTRL2, CPETRL2

Gene Name: CLDN7

Gene ID: 1366
Primary Accession: O95471
Other Accession: NP_001171951.1;NP_001298.3;NP_001171952.1
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.