CLDND1 Polyclonal Antibody

Background:
CLDND1 (claudin domain containing 1), also known as C3orf4 or HSPC174, is a 253 amino acid multi-pass membrane protein that is expressed at high levels in adult brain and at lower levels in adult heart. Existing as two alternatively spliced isoforms, CLDND1 is encoded by a gene that maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3.

Research Area: Cell Biology, Neuroscience

Synonyms:
C3orf4, Chromosome 3 open reading frame 4, Claudin domain containing 1, Claudin domain containing 1 protein, GENX 3745, Membrane protein GENX3745, MGC111162, MGC3316, MGC9861, OTTHUMP00000217407, OTTHUMP00000217408, OTTHUMP00000217423, OTTHUMP00000217424, OTTHUMP00000217562, OTTHUMP00000217563, OTTHUMP00000217584, OTTHUMP00000217585, OTTHUMP00000217586, OTTHUMP00000217587, OTTHUMP00000217609, OTTHUMP00000217610, OTTHUMP00000217611, OTTHUMP00000217622, OTTHUMP00000217623, OTTHUMP00000217625, OTTHUMP00000217627, OTTHUMP00000217628, OTTHUMP00000217638

Immunogen: Recombinant protein of human CLDND1

Swissprot: Q9NY35
Gene Accession: BC001757

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.2 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-99348