Cleaved-Caspase 6 p18 rabbit polyclonal, anti-human, rat

Backgroud: Caspase-6 (Mch2) is one of the major executioner caspases functioning in cellular apoptotic processes. Upon apoptotic stimulation, initiator caspases such as caspase-9 are cleaved and activated. The activated upstream caspases further process downstream executioner caspases, such as caspase-3 and caspase-6, by cleaving them into large and small subunits, thereby initiating a caspase cascade leading to apoptosis. One of the major targets for caspase-6 is the membrane associated protein lamin A.

Synonyms: CASP6, MCH2, Caspase-6, CASP-6, Apoptotic protease Mch-2

Gene Name: CASP6

Gene ID: 839

SwissProt ID: P55212

Purification: Affinity Chromatography

Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.