Cleaved-Ephrin-A2 (N188) rabbit polyclonal, anti-human, mouse

Backgroud: This gene encodes a member of the ephrin family. The protein is composed of a signal sequence, a receptor-binding region, a spacer region, and a hydrophobic region. The EPH and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. Posttranslational modifications determine whether this protein localizes to the nucleus or the cytoplasm. [provided by RefSeq, Jul 2008],similarity:Belongs to the ephrin family.,subunit:Binds to the receptor tyrosine kinases EPHA3, EPHA4 and EPHA5.,

Synonyms: EFNA2, EPLG6, LERK6, Ephrin-A2, EPH-related receptor tyrosine kinase ligand 6, LERK-6, HEK7 ligand, HEK7-L

Gene Name: EFNA2

Gene ID: 1943

SwissProt ID: O43921

Purification: Affinity purification

Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.