Cleaved-Integrin α7 LC (E959) Polyclonal Antibody

Background:
integrin subunit alpha 7(ITGA7) Homo sapiens The protein encoded by this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. They mediate a wide spectrum of cell-cell and cell-matrix interactions, and thus play a role in cell migration, morphologic development, differentiation, and metastasis. This protein functions as a receptor for the basement membrane protein laminin-1. It is mainly expressed in skeletal and cardiac muscles and may be involved in differentiation and migration processes during myogenesis. Defects in this gene are associated with congenital myopathy. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Feb 2009],

Alternative Names:
ITGA7, Integrin alpha-7

Immunogen: The antiserum was produced against synthesized peptide derived from human ITGA7. AA range:940-989

Isotype: Rabbit

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml

Observed band: 25

GeneID: ITGA7

Storage: -20°C/1 year

NOTE: For Research Use Only