Cleaved-Thrombin APII (R327) Polyclonal Antibody

Background:
coagulation factor II, thrombin(F2) Homo sapiens Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Peptides derived from the C-terminus of this protein have antimicrobial activity against E. coli and P. aeruginosa. Mutations in F2 lead to various forms of thrombosis and dysprothrombinemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015],

Alternative Names:
F2, Prothrombin, Coagulation factor II

Immunogen: The antiserum was produced against synthesized peptide derived from human THRB. AA range:278-327

Isotype: Rabbit

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml

Observed band: 19

GeneID: F2

Storage: -20°C/1 year

NOTE: For Research Use Only