LOK polyclonal, anti-human
€470.00
In stock
SKU
AC-AP70761
Background:
Serine/threonine-protein kinase involved in regulation of lymphocyte migration. Phosphorylates MSN, and possibly PLK1. Involved in regulation of lymphocyte migration by mediating phosphorylation of ERM proteins such as MSN. Acts as a negative regulator of MAP3K1/MEKK1. May also act as a cell cycle regulator by acting as a polo kinase kinase: mediates phosphorylation of PLK1 in vitro; however such data require additional evidences in vivo.
Other Names:
STK10; LOK; Serine/threonine-protein kinase 10; Lymphocyte-oriented kinase
Antigen Type: synthetic peptide
Antigen Type: STK10
Gene ID: 6793
Primary Accession: O94804
Serine/threonine-protein kinase involved in regulation of lymphocyte migration. Phosphorylates MSN, and possibly PLK1. Involved in regulation of lymphocyte migration by mediating phosphorylation of ERM proteins such as MSN. Acts as a negative regulator of MAP3K1/MEKK1. May also act as a cell cycle regulator by acting as a polo kinase kinase: mediates phosphorylation of PLK1 in vitro; however such data require additional evidences in vivo.
Other Names:
STK10; LOK; Serine/threonine-protein kinase 10; Lymphocyte-oriented kinase
Antigen Type: synthetic peptide
Antigen Type: STK10
Gene ID: 6793
Primary Accession: O94804
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