CLEC14A polyclonal, anti-human, mouse, rat

CLEC14A polyclonal, anti-human, mouse, rat

€305.00
In stock
SKU
BS60339
Catalog Number: BS60339
Size: 50 ul, 100 ul
Isotype: rabbit IgG
Applications: WB

Datasheet
Background:
CLEC-14A (C-type lectin domain family 14 member A), also known as EGFR-5 (epidermal growth factor receptor 5) or CEG1, is a 490 amino acid single-pass type I membrane protein that contains one C-type lectin domain and an EGF-like domain. The gene encoding CLEC-14A maps to human chromosome 14, which houses over 700 genes and comprises nearly 3.5% of the human genome. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer’s disease (AD). The SERPINA1 gene is also located on chromosome 14 and, when defective, leads to the genetic disorder α1-antitrypsin deficiency, which is characterized by severe lung complications and liver dysfunction.

Alternative Name:
C-type lectin domain family 14 member A, Epidermal growth factor receptor 5, EGFR-5, CLEC14A, C14orf27, EGFR5, UNQ236/PRO269

Application Dilution: WB: 1:500~1:1000

Specificity: CLEC14A polyclonal antibody detects endogenous levels of CLEC14A protein.

Immunogen:
A synthetic peptide corresponding to residues in Human CLEC14A.

MW: ~ 62 kDa

Swis Prot.: Q86T13

Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.

Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

For research use only, not for use in diagnostic procedure.
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