CLEC7A Antibody (N-term) Blocking peptide
€363.00
In stock
SKU
AC-BP13369a
Background:
This gene encodes a member of the C-type lectin/C-typelectin-like domain (CTL/CTLD) superfamily. The encoded glycoproteinis a small type II membrane receptor with an extracellular C-typelectin-like domain fold and a cytoplasmic domain with animmunoreceptor tyrosine-based activation motif. It functions as apattern-recognition receptor that recognizes a variety ofbeta-1,3-linked and beta-1,6-linked glucans from fungi and plants,and in this way plays a role in innate immune response. Alternatetranscriptional splice variants, encoding different isoforms, havebeen characterized. This gene is closely linked to other CTL/CTLDsuperfamily members on chromosome 12p13 in the natural killer genecomplex region.
Other Names:
C-type lectin domain family 7 member A, Beta-glucan receptor, C-type lectin superfamily member 12, Dendritic cell-associated C-type lectin 1, DC-associated C-type lectin 1, Dectin-1, CLEC7A, BGR, CLECSF12, DECTIN1
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13369a was selected from the N-term region of CLEC7A. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: CLEC7A (HGNC:14558)
Gene ID: 64581
Primary Accession: Q9BXN2
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
This gene encodes a member of the C-type lectin/C-typelectin-like domain (CTL/CTLD) superfamily. The encoded glycoproteinis a small type II membrane receptor with an extracellular C-typelectin-like domain fold and a cytoplasmic domain with animmunoreceptor tyrosine-based activation motif. It functions as apattern-recognition receptor that recognizes a variety ofbeta-1,3-linked and beta-1,6-linked glucans from fungi and plants,and in this way plays a role in innate immune response. Alternatetranscriptional splice variants, encoding different isoforms, havebeen characterized. This gene is closely linked to other CTL/CTLDsuperfamily members on chromosome 12p13 in the natural killer genecomplex region.
Other Names:
C-type lectin domain family 7 member A, Beta-glucan receptor, C-type lectin superfamily member 12, Dendritic cell-associated C-type lectin 1, DC-associated C-type lectin 1, Dectin-1, CLEC7A, BGR, CLECSF12, DECTIN1
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13369a was selected from the N-term region of CLEC7A. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: CLEC7A (HGNC:14558)
Gene ID: 64581
Primary Accession: Q9BXN2
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
| Is Featured? | No |
|---|
Write Your Own Review