CLEC7A polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS71364
Background:
Lectin that functions as pattern receptor specific for beta-1,3-linked and beta-1,6-linked glucans, such as cell wall constituents from pathogenic bacteria and fungi. Necessary for the TLR2-mediated inflammatory response and for TLR2-mediated activation of NF-kappa-B. Enhances cytokine production in macrophages and dendritic cells. Mediates production of reactive oxygen species in the cell. Mediates phagocytosis of C.albicans conidia. Binds T-cells in a way that does not involve their surface glycans and plays a role in T-cell activation. Stimulates T-cell proliferation.
Alternative Name:
C-type lectin domain family 7 member A, Dectin-1, :CLEC7A, BGR, CLECSF12, DECTIN1, UNQ539/PRO1082
Application Dilution: WB: 1:500 - 1:2000
Specificity: CLEC7A polyclonal antibody detects endogenous levels of CLEC7A protein.
Immunogen:
A synthetic peptide of human CLEC7A.
MW: ~ 28 kDa
Swis Prot.: Q9BXN2
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Lectin that functions as pattern receptor specific for beta-1,3-linked and beta-1,6-linked glucans, such as cell wall constituents from pathogenic bacteria and fungi. Necessary for the TLR2-mediated inflammatory response and for TLR2-mediated activation of NF-kappa-B. Enhances cytokine production in macrophages and dendritic cells. Mediates production of reactive oxygen species in the cell. Mediates phagocytosis of C.albicans conidia. Binds T-cells in a way that does not involve their surface glycans and plays a role in T-cell activation. Stimulates T-cell proliferation.
Alternative Name:
C-type lectin domain family 7 member A, Dectin-1, :CLEC7A, BGR, CLECSF12, DECTIN1, UNQ539/PRO1082
Application Dilution: WB: 1:500 - 1:2000
Specificity: CLEC7A polyclonal antibody detects endogenous levels of CLEC7A protein.
Immunogen:
A synthetic peptide of human CLEC7A.
MW: ~ 28 kDa
Swis Prot.: Q9BXN2
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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