CLEC7A polyclonal, anti-human, mouse, rat

Background:
This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. The encoded glycoprotein is a small type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif. It functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region.

Synonyms: BGR, CANDF4, CD369, CLECSF12, DECTIN1, SCARE2

Cellular Location: Cell membrane Cytoplasm Single-pass type II membrane protein

Immunogen:
A synthetic peptide of human CLEC7A

Gene Symbol: CLEC7A

Gene ID: 64581

Swiss prot: Q9BXN2

Calculated MW: 28kDa

Recommended dilution:
WB 1:500-2000

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.