CLEC7A Polyclonal Antibody

Background:
This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. The encoded glycoprotein is a small type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif. It functions as a pattern-recognition receptor that recognizes a variety of beta-1, 3-linked and beta-1, 6-linked glucans from fungi and plants, and in this way plays a role in innate immune response. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region.

Research Area: Cancer, Immunology

Synonyms:
CLEC7A, BGR, CANDF4, CD369, CLECSF12, DECTIN1, SCARE2

Immunogen: A synthetic peptide of human CLEC7A (NP_922938.1).

Swissprot: Q9BXN2
Gene ID: 64581

Calculated MW: 5 kDa/8 kDa/13-27 kDa
Observed MW: 31 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.