NPRL2 polyclonal, anti-human, mouse, rat
€470.00
In stock
SKU
AC-AP73269
Background:
As a component of the GATOR1 complex functions as an inhibitor of the amino acid-sensing branch of the TORC1 pathway. The GATOR1 complex strongly increases GTP hydrolysis by RRAGA and RRAGB within RRAGC-containing heterodimers, thereby deactivating RRAGs, releasing mTORC1 from lysosomal surface and inhibiting mTORC1 signaling. The GATOR1 complex is negatively regulated by GATOR2 the other GATOR subcomplex in this amino acid-sensing branch of the TORC1 pathway.
Other Names:
NPRL2; TUSC4; Nitrogen permease regulator 2-like protein; NPR2-like protein; Gene 21 protein; G21 protein; Tumor suppressor candidate 4
Antigen Type: synthetic peptide
Antigen Type: NPRL2 {ECO:0000303|PubMed:18616680, ECO:0000312|HGNC:HGNC:24969}
Gene ID: 10641
Primary Accession: Q8WTW4
As a component of the GATOR1 complex functions as an inhibitor of the amino acid-sensing branch of the TORC1 pathway. The GATOR1 complex strongly increases GTP hydrolysis by RRAGA and RRAGB within RRAGC-containing heterodimers, thereby deactivating RRAGs, releasing mTORC1 from lysosomal surface and inhibiting mTORC1 signaling. The GATOR1 complex is negatively regulated by GATOR2 the other GATOR subcomplex in this amino acid-sensing branch of the TORC1 pathway.
Other Names:
NPRL2; TUSC4; Nitrogen permease regulator 2-like protein; NPR2-like protein; Gene 21 protein; G21 protein; Tumor suppressor candidate 4
Antigen Type: synthetic peptide
Antigen Type: NPRL2 {ECO:0000303|PubMed:18616680, ECO:0000312|HGNC:HGNC:24969}
Gene ID: 10641
Primary Accession: Q8WTW4
| Is Featured? | No |
|---|
Write Your Own Review