CLIC4 Polyclonal Antibody

Background:
Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. CLIC4 is a p53- and tumor necrosis factor alpha-regulated cytoplasmic and mitochondrial protein that belongs to the CLIC family of intracellular chloride channels. CLICs have actions distinct from traditional cell membrane chloride channels, including formation of ion channels in intracellular organelles and roles in membrane trafficking, apoptosis, and cell differentiation.

Research Area: Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Metabolism, Signal Transduction

Synonyms:
Chloride intracellular channel 4, Chloride intracellular channel 4 (mitochondrial), Chloride intracellular channel 4 like, Chloride intracellular channel protein 4, Clic4, CLIC4, CLIC4L, DKFZP566G223, FLJ38640, H1, HUH1, Intracellular chloride ion channel protein p64H1, MC3S5, mtCLIC, p64H1

Immunogen: Synthetic peptide of human CLIC4

Swissprot: Q9Y696
Gene Accession: NP039234

Calculated MW: 29 kDa
Observed MW: Refer to figures

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.6 mg/mL
Dilution: WB 1:500-1:2000, ELISA 1:2000-1:5000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.