CMA1 polyclonal, anti-human

Quantity: 100 µg

Background:
Chymase is a major secreted protease of mast cells with suspected roles in vasoactive peptide generation, extracellular matrix degradation, and regulation of gland secretion. This gene product is a chymotryptic serine proteinase that belongs to the peptidase family S1. Chymase is mapped to 14q12. It is expressed in mast cells and thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides. In the heart and blood vessels, this protein, rather than angiotensin converting enzyme, is largely responsible for converting angiotensin I to the vasoactive peptide angiotensin II.

Description:
Rabbit IgG polyclonal antibody for Chymase (CMA1) detection. Tested with WB, IHC-P in Human.

Synonyms:
Alpha-chymase antibody, Chymase 1 antibody, Chymase 1 mast cell antibody, Chymase antibody, Chymase, heart antibody, Chymase, mast cell antibody, CMA1 antibody, CMA1_HUMAN antibody, CYH antibody, CYM antibody, EC 3.4.21.39 antibody, Mast cell chymase 1 antibody, Mast cell protease 3 antibody, Mast cell protease 5 antibody, Mast cell protease I antibody, Mast cell protease III antibody, Mcp-5 antibody, MCP3P antibody, Mcpt5 antibody, MGC119890 antibody, MGC119891 antibody, MMCP-5 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E.coli-derived human CMA1 recombinant protein (Position: I22-N247). Human CMA1 shares 75% and 74% amino acid (aa) sequence identity with mouse and rat CMA1, respectively.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.