CNGB1 rabbit polyclonal, anti-human, mouse, rat

Backgroud: Subunit of cyclic nucleotide-gated (CNG) channels, nonselective cation channels, which play important roles in both visual and olfactory signal transduction. When associated with CNGA1, it is involved in the regulation of ion flow into the rod photoreceptor outer segment (ROS), in response to light-induced alteration of the levels of intracellular cGMP.Isoform GARP2 is a high affinity rod photoreceptor phosphodiesterase (PDE6)-binding protein that modulates its catalytic properties: it is a regulator of spontaneous activation of rod PDE6, thereby serving to lower rod photoreceptor 'dark noise' and allowing these sensory cells to operate at the single photon detection limit.

Synonyms: CNG4, GAR1, GARP, RP45, CNCG2, CNCG4, GARP2, RCNC2, RCNCb, CNCG3L, CNGB1B, RCNCbeta

Gene Name: CNGB1

Gene ID: 1258

SwissProt ID: Q14028

Purification: Affinity Chromatography

Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.