CNGB3 N-terminal region polyclonal, anti-human

Background:
Visual signal transduction is mediated by a G-protein coupled cascade using cGMP as second messenger. This protein can be activated by cGMP which leads to an opening of the cation channel and thereby causing a depolarization of rod photoreceptors. Induced a flickering channel gating, weakened the outward rectification in the presence of extracellular calcium, increased sensitivity for L-cis diltiazem and enhanced the cAMP efficiency of the channel when coexpressed with CNGA3 (By similarity). Essential for the generation of light-evoked electrical responses in the red-, green- and blue sensitive cones.

Other Names:
Cyclic nucleotide-gated cation channel beta-3, Cone photoreceptor cGMP-gated channel subunit beta, Cyclic nucleotide-gated cation channel modulatory subunit, Cyclic nucleotide-gated channel beta-3, CNG channel beta-3, CNGB3

Immunogen:
The immunogen for Anti-CNGB3 antibody is: synthetic peptide directed towards the N-terminal region of Human CNGB3

Gene Name:
CNGB3 {ECO:0000303|PubMed:37463923}
Gene Name:
54714
NCBI Accession:
NP_061971
Primary Accession: Q9NQW8
Other Accession: NP_061971
Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.